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Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma
Authors:Madeline N. Hayes  Karin McCarthy  Alexander Jin  Mariana L. Oliveira  Sowmya Iyer  Sara P. Garcia  Sivasish Sindiri  Berkley Gryder  Zainab Motala  G. Petur Nielsen  Jean-Paul Borg  Matt van de Rijn  David Malkin  Javed Khan  Myron S. Ignatius  David M. Langenau
Affiliation:1. Molecular Pathology, Cancer Center, and Regenerative Medicine, Massachusetts General Hospital Research Institute, Boston, MA 02129, USA;2. Harvard Stem Cell Institute, Cambridge, MA 02139, USA;3. Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal;4. Oncogenomics Section, Center for Cancer Research, National Cancer Institute, NIH, 37 Convent Drive, Bethesda, MD 20892, USA;5. Division of Hematology/Oncology, Hospital for Sick Children and Department of Pediatrics, University of Toronto, Toronto, ON M5G1X8, Canada;6. Department of Pathology, Massachusetts General Hospital, Boston, MA 02129, USA;7. Centre de Recherche en Cancérologie de Marseille, Aix Marseille Univ UM105, Inst Paoli Calmettes, UMR7258 CNRS, U1068 INSERM, “Cell Polarity, Cell signalling and Cancer - Equipe labellisée Ligue Contre le Cancer,” Marseille, France;8. Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA;9. Molecular Medicine and Greehey Children’s Cancer Research Institute, UTHSCSA, San Antonio, TX 78229, USA
Abstract:
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  • Keywords:muscle  cancer  planar cell polarity  RhoA  zebrafish
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