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Solid state fermentation for L-glutamic acid production using Brevibacterium sp.
Authors:K Madhavan Nampoothiri  Ashok Pandey
Institution:(1) Biotechnology Unit, Regional Research Laboratory, CSIR, 695 019 Trivandrum, India;(2) Laboratoire de Microbiologie, Univérsité Louis Pasteur, CNRS, URA ncompfn 1481, 67083 Strasbourg, France
Abstract:Summary Solid state fermentation system was used to cultivate Brevibacterium sp. on sugar cane bagasse impregnated with a medium containing glucose, urea, mineral salts and vitamins for producing L-glutamic acid. Maximum yields (80 mg glutamic acid per g dry bagasse with biomass and substrate - mg/gds) were obtained when bagasse of mixed particle size was moistened at 85–90 % mositure level with the medium containing 10 % glucose. This is the first report on the cultivation of Brevibacterium sp. in solid cultures for production of glutamic acid.
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