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Cell growth and division: a deterministic/probabilistic model of the cell cycle
Authors:John J. Tyson  Kenneth B. Hannsgen
Affiliation:(1) Departments of Biology and Mathematics, Virginia Polytechnic Institute and State University, 24061 Blacksburg, VA, USA
Abstract:A model of the cell cycle, incorporating a deterministic cell-size monitor and a probabilistic component, is investigated. Steady-state distributions for cell size and generation time are calculated and shown to be globally asymptotically stable. These distributions are used to calculate various statistical quantities, which are then compared to known experimental data. Finally, the results are compared to distributions calculated from a Monte-Carlo simulation of the model.
Keywords:Cell division cycle  size distribution  generation time distribution
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