ESR evidence of superoxide radical dismutation by human ceruloplasmin |
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| Authors: | Andrzej Pḱlonka Diana Metodiewa Alojzy Zgirski Maria Hilewicz Wanda Leyko |
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| Institution: | Institute of Applied Radiation Chemistry Technical University of ?Lód?, 93-590 ?Lód?, Poland;Institute of Biochemistry and Biophysics University of ?Lód?, 90-237 ?Lód?, Poland |
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| Abstract: | The formation of the paramagnetic complex between human ceruloplasmin and radiation produced superoxide radicals was observed by the ESR method at low temperatures. The disappearance of the complex without changes in the oxidation state of copper give the direct evidence that ceruloplasmin, the major antioxidant in serum, is able to dismutate superoxide radicals. |
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