Genome sequence of Mycobacterium bovis BCG Moreau, the Brazilian vaccine strain against tuberculosis |
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| Authors: | Gomes Leonardo H F Otto Thomas D Vasconcellos Erico A Ferrão Patrícia M Maia Renata M Moreira Aline S Ferreira Marcelo A Castello-Branco Luiz R R Degrave Wim M Mendonça-Lima Leila |
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| Institution: | 1Laboratório de Genômica Funcional e Bioinformática, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil;2Centro de Pesquisas Arlindo de Assis, Fundação Ataulpho de Paiva, Rio de Janeiro, Brazil |
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| Abstract: | Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only vaccine available against tuberculosis, and the strains used worldwide represent a family of daughter strains with distinct genotypic characteristics. Here we report the complete genome sequence of M. bovis BCG Moreau, the strain in continuous use in Brazil for vaccine production since the 1920s. |
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