A facile synthesis of 1-(5'-O-acetyl-3'-O-benzyl-beta-D-xylofuranosyl)thymidine: a potentially viable intermediate for the preparation of the anti-AIDS drugs, AZT and D4T |
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| Authors: | Ning J Kong F |
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| Affiliation: | Research Center for Eco-Environmental Sciences, Academia Sinica, Beijing, PR China. |
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| Abstract: | ![]()
The title compound has been synthesized by smooth condensation of 1,2-anhydro-5-O-acetyl-3-O-benzyl-alpha-D-xylofuranose, obtained from D-xylose through a series of mild and effective reactions, with activated thymine in the absence of catalyst. |
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