The methyltrienolone binding protein of JEG-3 cells and human placenta is localized within the nucleus and is tightly associated with chromatin. |
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| Authors: | J O Macaulay G L Warne Z S Krozowski |
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| Affiliation: | Department of Endocrinology and Diabetes, Royal Children's Hospital, Parkville, Australia. |
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| Abstract: | Human placenta contains the methyltrienolone binding protein (MTBP), an androgen binding protein which is distinct from the androgen receptor. This study demonstrates that the human choriocarcinoma cell line (JEG-3) also contains the MTBP and that in both human placenta and JEG-3 cells the MTBP is located exclusively in the nucleus and in particular is associated with DNase 1 resistant chromatin. |
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