| Abstract: | A study was made of the accumulation of lipoperoxidation products and O2- generation induced by cumene hydroperoxide in mitochondria of irradiated rat liver. O2- generation and formation of lipoperoxidation products were found to be connected with the function of mitochondrial P-450 cytochrome. During the first 24 h following X-irradiation of rats with a dose of 10 Gy, the rate of O2- generation sharply increased and mitochondria could not regulate the intensity of lipoperoxidation with incubation medium tonicity being altered. |
