Antifungal activity of Δ3-alstovenine, a plant alkaloid isolated fromAlstonia venenata |
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Authors: | S K Singh B K Sarma J S Srivastava U P Singh A B Ray |
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Institution: | (1) Department of Mycology and Plant Pathology, Institute of Agricultural Sciences, Banaras Hindu University, 221 005 Varanasi, India;(2) Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, 221 005 Varanasi, India |
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Abstract: | A plant quaternary alkaloid Δ3-alstovenine inhibited the spore germination of most of the fungi tested at concentration of 250–1000 mg/L. Saprophytic and
biotrophic fungi were equally sensitive to the alkaloid.Cercospora sp. was the most sensitive as 100% inhibition of spore germination was observed at 250 mg/L.Alternaria species,Curvularia species andFusarium udum were not affected even at 1000 mg/L. |
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