Sara Bruschini, Simona di Martino, Gennaro Ciliberto, and Rita Mancini contributed equally to this work.;2. Phatology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy

Sara Bruschini, Simona di Martino, Gennaro Ciliberto, and Rita Mancini contributed equally to this work.;3. High Resolution NMR Unit, Core Facilities, Istituto Superiore di Sanità, Rome, Italy;4. Department of Clinical and Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy;5. Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy;6. Phatology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy;7. Preclinical Models and New Therapeutic Agents Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy;8. Thoracic Surgery Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy;9. Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy;10. Tissue Engineering and Chemistry for Engineering Lab, Department of Engineering, University Campus Bio-Medico, Rome, Italy;11. UCS Diagnostic S.r.l., Rome, Italy;12. Section of Pathology, University Hospital Campus Bio-Medico of Rome, Rome, Italy;13. Scientific Direction, IRCCS Regina Elena National Cancer Institute, Rome, Italy

Sara Bruschini, Simona di Martino, Gennaro Ciliberto, and Rita Mancini contributed equally to this work.