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Two novel steroidal alkaloid glycosides from the seeds of Lycium barbarum |
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| Authors: | Wang Kun Sasaki Tatsunori Li Wei Li Qin Wang Yinghua Asada Yoshihisa Kato Hiroyoshi Koike Kazuo |
| Affiliation: | Faculty of Pharmaceutical Sciences, Toho University, Funabashi, Chiba, Japan. |
| Abstract: | Two novel steroidal alkaloid glycosides, lycioside A (1) and lycioside B (2) were isolated from the seeds of Lycium barbarum. Their structures were determined by various spectroscopic analyses. Compounds 1 and 2 showed inhibitory activities with the IC(50) values of 75.3 and 72.8 μM against rat intestinal sucrase, and 63.4 and 59.1 μM against rat intestinal maltase. |
| Keywords: | Lycium barbarum Steroids Glycosides Alkaloids Lyciosides A and B Inhibitors |
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