Vitamin D3 sulfoconjugate in pregnant and lactating mother rats after dosing with 3H vitamin D3 |
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| Authors: | N Le Boulch C Gulat-Marnay L Miravet M Laromiquière Y Raoul |
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| Affiliation: | 1. Laboratoire de Physiologie, Université Paris V, 4 avenue de l''Observatoire 75006 ParisFrance;2. Unité de Recherche sur le Métabolisme Phospho-calcique. Centre André Lichtwitz, 6 rue Guy Patin, 75010 ParisFrance |
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| Abstract: | Twenty four hours after dosing of pregnant rats with 3H vitamin D3 i.v. the sulfoconjugate was detected only in the kidney. In contrast, 24 or 48 hours after 3H vitamin D3 i.v. dosing the vitamin D3 sulfoconjugate was detected in the plasma, liver, kidney and mammary glands of lactating mother rats. |
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| Keywords: | Estradiol 1,3,5 (10)-estratriene,3,17β-diol Progesterone (P) 4-pregnene-3,20-dione Medroxyprogesterone acetate (MPA) 17-acetoxy-6α-methylpregn-4-ene-3,20-dione 20α dihydroprogesterone (20αDHP) 20α-hydroxy-4-pregnene-3-one 5α-dihydroprogesterone (5αDHP) 5α-pregnane-3,20-dione 5β-dihydroprogesterone (5βDHP) 5β-pregnane-3,20-dione (20αHSD) 20α-hydroxysteroid oxidoreductase (3βHSD) 3β-hydroxysteroid oxidoreductase (TCA) Trichloracetic acid |
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