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Control of cultivation processes for recombinant protein production: a review |
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| Authors: | Stefan Gnoth Marco Jenzsch Rimvydas Simutis Andreas Lübbert |
| Institution: | (1) Institute for Biochemistry and Biotechnology, Martin-Luther University, Halle-Wittenberg, Germany;(2) Institute of Automation and Control Systems, Kaunas University of Technology, Kaunas, Lithuania |
| Abstract: | The current state-of-the-art in control of cultivation processes for recombinant protein production is examined including the quantitative knowledge that can be activated for this purpose and the measurement techniques that can be employed for control at industrial manufacturing sites. |
| Keywords: | Fermentation processes Process modeling Control Supervision Fault detection Soft-sensing Neural networks |
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