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Critical role of Syk-dependent STAT1 activation in innate antiviral immunity
Authors:Shasha Liu  Yuan Liao  Biao Chen  Yuhai Chen  Ziding Yu  Haitao Wei  Lianfeng Zhang  Shile Huang  Paul B. Rothman  George Fu Gao  Ji-Long Chen
Affiliation:1. CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing 100101, China;2. Key Laboratory of Fujian-Taiwan Animal Pathogen Biology, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China;3. University of Chinese Academy of Sciences, Beijing 100049, China;4. Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Comparative Medical Center, Peking Union Medical College, Beijing 100021, China;5. Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA;6. Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Abstract:
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  • Keywords:STAT1  Syk  influenza virus  innate immunity  RIG-I  MAVS  cytokine
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