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The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells
Authors:Michael Pryszlak  Mallory Wiggans  Xin Chen  Julia E. Jaramillo  Sarah E. Burns  Laura M. Richards  Trevor J. Pugh  David R. Kaplan  Xi Huang  Peter B. Dirks  Bret J. Pearson
Affiliation:1. The Hospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, ON M5G 0A4, Canada;2. University of Toronto, Department of Molecular Genetics, Toronto, ON M5S 1A8, Canada;3. Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada;4. The Hospital for Sick Children, Arthur and Sonia Labatt Brain Tumor Research Centre, Toronto, ON M5G 0A4, Canada;5. Department of Medical Biophysics, University of Toronto, ON M5G 1L7, Canada;6. Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada
Abstract:
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  • Keywords:adult stem cells  stemness  planarians  glioblastoma  comparative genomics  evolution of stem cells  DDX56  cancer stem cells  RNAi
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