TB or Not TB: how Mycobacterium tuberculosis may evade drug treatment |
| |
Authors: | Friedberg Errol C Fischhaber Paula L |
| |
Affiliation: | Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA. |
| |
Abstract: | In this issue of Cell, a study by Valerie Mizrahi and her colleagues suggests that a putative error-prone DNA polymerase encoded by the dnaE2 gene of Mycobacterium tuberculosis may bypass certain types of DNA base damage, generating mutations. This may be an important mechanism for generating drug-resistant strains of M. tuberculosis. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|