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Trypanosoma cruzi: a stage-specific calpain-like protein is induced after various kinds of stress
Authors:Giese Viviane  Dallagiovanna Bruno  Marchini Fabricio K  Pavoni Daniela P  Krieger Marco A  Goldenberg Samuel
Affiliation:Instituto Carlos Chagas-Fiocruz, Curitiba, PR, Brasil.
Abstract:Calpains are calcium-dependent cysteine proteinases found in all living organisms and are involved in diverse cellular processes. Calpain-like proteins have been reported after in silico analysis of the Tritryps genome and are believed to play important roles in cell functions of trypanosomatids. We describe the characterization of a member of this family, which is differentially expressed during the life-cycle of Trypanosoma cruzi.
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