Trypanosoma cruzi: a stage-specific calpain-like protein is induced after various kinds of stress |
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Authors: | Giese Viviane Dallagiovanna Bruno Marchini Fabricio K Pavoni Daniela P Krieger Marco A Goldenberg Samuel |
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Affiliation: | Instituto Carlos Chagas-Fiocruz, Curitiba, PR, Brasil. |
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Abstract: | Calpains are calcium-dependent cysteine proteinases found in all living organisms and are involved in diverse cellular processes. Calpain-like proteins have been reported after in silico analysis of the Tritryps genome and are believed to play important roles in cell functions of trypanosomatids. We describe the characterization of a member of this family, which is differentially expressed during the life-cycle of Trypanosoma cruzi. |
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