Ultrastructural alterations in cardiac and skeletal muscles in experimental diabetes mellitus |
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| Authors: | I Balogh M Z Koltai G Pogátsa |
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| Institution: | Department of Forensic Medicine, Semmelweis Medical School, Budapest, Hungary. |
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| Abstract: | In 18 alloxan-diabetic and 12 metabolically healthy dogs cardiac and skeletal muscles have been studied electronmicroscopically. Myopathy-like alterations, as widening of Z band material, alterations of mitochondria as well as of collagen fibers were observed in the diabetic myocardium. In skeletal muscle nemalin bodies were found. These latter alterations don't develop in insulin-treated diabetic state. |
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