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Toxic epidermal necrolysis associated with radiotherapy and phenytoin in a patient with non-Hodking's lymphoma: A case report |
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| Authors: | Fatma Keklik Melda C?mert ?zkan Gizem Kocaba? Yenipazar Banu Yaman Güray Saydam Fahri ?ahin |
| Affiliation: | aEge University, School of Medicine, Department of Internal Medicine, Izmir, Turkey;bDepartment of Hematology, Izmir, Turkey;cDepartment of Dermatology, Izmir, Turkey;dDepartment of Pathology, Izmir, Turkey |
| Abstract: | Toxic epidermal necrolysis (TEN) is a disease which is characterized by fever and desquamation of the skin and mucosal membranes. It is usually related with drugs, especially aromatic anticonvulsants which are recognized as the most common cause of this disorder. Cranial irradiation may act as a precipitating factor along with anticonvulsants for the development of TEN. We report a 28-year-old patient with central nervous system (CNS) relapsed non-Hodgkin lymphoma (NHL) who developed TEN after cranial radiotherapy and concurrent phenytoin treatment. |
| Keywords: | Radiotherapy Fenitoin Toxic epidermal necrolysis |