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Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity
Institution:1. Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK;2. Systems Immunity University Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK;3. Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK;4. Department of Gastroenterology & Hepatology, University Hospital of Wales, Cardiff CF14 4XW, UK
Abstract:
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  • Keywords:T cells  SARS-CoV-2  coronavirus  COVID-19  HLA class II  antigen presentation  immune escape  immune memory  crystallography  CP: Immunology
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