Hypoglycemic Activity of <Emphasis Type="Italic">Grifola frondosa</Emphasis> Rich in Vanadium |
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| Authors: | Bo Cui Linna Han Jingran Qu Yingtao Lv |
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| Institution: | (1) College of Food and Bioengineering, Shandong Institute of Light Industry, Jinan, 250353, People’s Republic of China;(2) School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, People’s Republic of China;(3) College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, People’s Republic of China; |
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| Abstract: | The hypoglycemic activity of fermented mushroom of Grifola frondosa rich in vanadium (GFRV) was studied in this paper. Alloxan- and adrenalin-induced hyperglycemic mice were used in the study.
The blood glucose and the HbA1c of the mice were analyzed respectively. After the mice were administered (ig) with GFRV, the
blood glucose and the HbA1c of alloxan-induced hyperglycemic mice decreased (p < 0.05, p < 0.01) and ascension of blood glucose induced by adrenalin was inhibited (p < 0.01). Also, the bodyweight of the alloxan-induced hyperglycemic mice was increased gradually. In the fermented mushroom
of G. frondosa, vanadium at lower doses in combination with G. frondosa induced significant decreases of the blood glucose and HbA1c levels in hyperglycemic mice. |
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