Antigenic variation of Newcastle disease viruses isolated from wild ducks in Japan |
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Authors: | M Kawamura K Nagata-Matsubara K Nerome N Yamane H Kida H Kodama H Izawa T Mikami |
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Institution: | Department of Epizootiology, Faculty of Veterinary Medicine, Hokkaido University. |
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Abstract: | Nineteen strains of Newcastle disease virus (NDV) isolated from wild ducks in Japan were placed into 4 distinct antigenic groups on the basis of their reactivities to 8 monoclonal antibodies against the HN molecule of NDV in hemagglutination inhibition tests. The NDV strains of duck origin were antigenically distinct from NDV-B1 and NDV-Miyadera originated from chickens, and varied in their virulence to chicken embryos. No apparent correlation was found between the antigenicity of the HN molecule and virulence. |
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