Caenorhabditis elegans senses bacterial autoinducers |
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Authors: | Beale Elmus Li Guigen Tan Man-Wah Rumbaugh Kendra P |
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Institution: | Department of Cell Biology, Texas Tech University Health Sciences Center, Texas 79430, USA. |
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Abstract: | Pseudomonas aeruginosa uses virulence factors controlled by quorum sensing (QS) to kill Caenorhabditis elegans. Here we show that C. elegans is attracted to the acylated homoserine lactones (AHSLs) that mediate QS in P. aeruginosa. Our data also indicate that C. elegans can distinguish AHSLs and may use them to mediate aversive or attractive learning. |
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