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The Extraneural Distribution of γ-Hydroxybutyrate
Authors:Thomas Nelson  Elaine Kaufman  John Kline  Louis Sokoloff
Affiliation:Laboratory of Cerebral Metabolism, Department of Health and Human Services, U.S. Public Health Service, Bethesda, Maryland, U.S.A.
Abstract:
Abstract— γ-Hydroxybutyrate has been found to be widely distributed in both neural and extraneural tissues in the rat. The kidney and brown fat have more than 10 times higher concentrations of y-hydroxybutyrate than does the brain. This observation suggests that γ-hydroxybutyrate may participate in the metabolism of many organs, and that GABA may not be the precursor in extraneural tissues.
Keywords:γ-Hydroxybutyrate    Tissue concentrations    Rat.
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