A Novel Approach for the Synthesis of seco C-Nucleoside Analogues |
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| Authors: | Laila F. Awad El Sayed H. El Ashry |
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| Affiliation: | Chemistry Department, Faculty of Science , Alexandria Unversity , Alexandria, Egypt |
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| Abstract: | Abstract The synthesis of 4-amino-3-(D-gluco- or D-galacto-pentitol-1.yl)-5-mercapto-1,2,4-triazoles and their conversion to the respective 6-methyl-3-(1,2,3,4,5-penta-O-acetyl-pentitol-1-yl)1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles have been achieved. The vicinal coupling constants were used to deduce the favored conformations. |
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