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Recurrent pneumonia with mild hypogammaglobulinemia diagnosed as X-linked agammaglobulinemia in adults |
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| Authors: | Kazuhiro Usui Yoji Sasahara Ryushi Tazawa Koichi Hagiwara Satoshi Tsukada Toshio Miyawaki Shigeru Tsuchiya Toshihiro Nukiwa |
| Institution: | (1) Department of Respiratory Oncology and Molecular Medicine, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan;(2) Department of Pediatric Oncology, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan;(3) Department of Medicine III, Osaka University Medical School, Osaka, Japan;(4) Department of Pediatrics, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan; |
| Abstract: | BackgroundX-linked agammaglobulinemia (XLA) is a humoral immunodeficiency caused by disruption of the Bruton's tyrosine kinase (BTK) gene. Typical XLA patients suffer recurrent and severe bacterial infections in childhood. |
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