Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients |
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| Authors: | Mouna Kallel Fatma Elloumi Abdelmajid Khabir Lilia Ghorbal Souhir Chaabouni Habib Amouri Mounir Frikha Jamel Daoud |
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| Affiliation: | aDepartment of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia;bCytology and Pathology, Habib Bourguiba University Hospital, Sfax, Tunisia;cGynecology and Obstetric, Hedi Chaker University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia;dMedical Oncology, Habib Bourguiba University Hospital, Sfax, Tunisia |
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| Abstract: | ![]()
PurposeTo define epidemiological, clinical, therapeutic and prognostic factors influencing survival of breast cancer in young women younger than 35 in southern Tunisia.Material and methodsThis is a retrospective study of 83 patients younger than 35 years and treated within tumors mammary committee of Sfax.ResultsThe mean age was 31.7 years. T2 stage, high grade with positive node tumors were frequent. Breast surgery was performed for 73 patients. Chemotherapy was neo-adjuvant, adjuvant and palliative for respectively 10, 62 and 13 patients. Radiotherapy was delivered for 65 patients with curative intent and for 8 metastatic patients. Endocrine therapy was adjuvant in 38 patients and palliative in 6 cases. The overall survival (OS) at 5 years was 66.8%. Pejorative prognostic factors in uni-variate analysis were clinical T stage (T3, T4), and the number of involved lymph nodes.ConclusionDespite adequate treatment, the prognosis of breast cancer in young women remains worse. Early diagnosis is necessary to promote outcome. |
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| Keywords: | Breast Cancer Young women Clinical Prognosis |
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