Design and evaluation of dihydroisoquinolines as potent and orally bioavailable human cytomegalovirus inhibitors |
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| Authors: | Chan L Stefanac T Turcotte N Hu Z Chen Y Bédard J May S Jin H |
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| Affiliation: | BioChem Pharma Inc., Laval, Québec, Canada. chanl@biochempharma.com |
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| Abstract: | Following the identification of first pass metabolism issues with our recently described anti-HCMV compounds, the naphthyridines and isoquinolines, we have designed a class of novel metabolically stable and orally bioavailable anti-HCMV agents, the dihydroisoquinolines. |
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