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A familial paracentric inversion: A short review of the current status |
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| Authors: | Philippus A. Venter Bronwin Dawson Joan L. Du Toit Esme L. Smith Nicolene Kritzinger Annette S. Landman Anna S. Cronje Johann Op't Hof |
| Affiliation: | (1) Department of Health and Welfare, Genetic Services, Private Bag X63, 0001 Pretoria, Republic of South Africa;(2) Department of Health and Welfare, Cytogenetics Laboratory, University of Potchefstroom for CHE, 2520 Potchefstroom, Republic of South Africa |
| Abstract: | Summary We present here a familial case of a paracentric inversion in man with a short review of the literature. A paracentric inversion of chromosome 10(q11q26) was found in the amniocytes drawn for advanced maternal age. The presence of the inversion was investigated in 35 family members in three generations. No recombinants were recognized. The significance of these data for appropriate genetic counselling and possible reproductive risks is discussed.Genetic Nurses, Department of Health and Welfare |
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