In-vitro evaluation of the antimicrobial activity of Bauhinia variegata,locally known as koiralo |
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| Authors: | Pokhrel Naba Raj Adhikari RP Baral MP |
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| Institution: | (1) Central Department of Microbiology, Tribhuvan University, P.O. Box 21489, Kirtipur, Kathmandu, Nepal;(2) Royal Nepal Academy of Science and Technology, Khumaltar, Lalitpur, Nepal |
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| Abstract: | Bauhinia variegata, commonly known as Koiralo is considered as medicinal plant in Nepal and India. The alcoholic extract of this plant was found to have antimicrobial activity against Bacillus subtilis (ATCC 6635) Pseudomonas aeruginosa (ATCC 27853), Salmonella typhi, Shigella dysenteriae, Staphylococcus aureus (ATCC 29213) and Vibrio cholerae. The largest zone of inhibition (18 mm) was found to be exhibited against B. subtilis. For this organism the minimum bactericidal concentration (MBC) of the crude extract was 0.39 mg/ml. The extract was found to be more effective against gram-positive than gram-negative bacteria. The antimicrobial activity of the extract was found to be decreased during purification. |
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| Keywords: | Antimicrobial activity Bauhinia variegata Koiralo minimum inhibitory concentration zone of inhibition |
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