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Non-identifiability of the Rayleigh damping material model in Magnetic Resonance Elastography
Authors:Andrii Y Petrov  J Geoffrey Chase  Mathieu Sellier  Paul D Docherty
Institution:1. Centre for Bioengineering, Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand;2. Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand
Abstract:Magnetic Resonance Elastography (MRE) is an emerging imaging modality for quantifying soft tissue elasticity deduced from displacement measurements within the tissue obtained by phase sensitive Magnetic Resonance Imaging (MRI) techniques. MRE has potential to detect a range of pathologies, diseases and cancer formations, especially tumors. The mechanical model commonly used in MRE is linear viscoelasticity (VE). An alternative Rayleigh damping (RD) model for soft tissue attenuation is used with a subspace-based nonlinear inversion (SNLI) algorithm to reconstruct viscoelastic properties, energy attenuation mechanisms and concomitant damping behavior of the tissue-simulating phantoms. This research performs a thorough evaluation of the RD model in MRE focusing on unique identification of RD parameters, μIμI and ρIρI.
Keywords:Magnetic Resonance Elastography  Nonlinear inversion  Rayleigh damping  Model identifiability  Mechanical properties  Medical imaging
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