| 复合诱变和抗性筛选利迪链菌素高产菌株 |
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| 引用本文： | 郭卫寰,李小兵,元英进.复合诱变和抗性筛选利迪链菌素高产菌株[J].微生物学通报,2007,34(5):0831-0835. |
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| 作者姓名： | 郭卫寰 李小兵 元英进 |
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| 作者单位： | 天津大学化工学院制药工程系,天津,300072 |
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| 摘 要： | 为解决利迪链霉菌生产能力低的问题,以Streptomyces lydicus AS4.2501-P28为出发菌株,应用紫外和吖啶橙诱变,结合抗生素的抗性筛选,得到稳定高产的S.lydicus AS4.2501-L8,发酵水平达到177.0μg/mL,较出发菌株提高了96.2%。
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| 关 键 词： | 利迪链霉菌 利迪链菌素 复合诱变 抗性筛选 |
| 文章编号： | 0253-2654（2007）05-0831-05 |
| 修稿时间： | 2007-01-05 |
Breeding of High Streptolydigin-Producing Strain by Complex Mutagenesis and Resistance Selection |
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| GUO Wei-Huan,LI Xiao-Bing and YUAN Ying-Jin.Breeding of High Streptolydigin-Producing Strain by Complex Mutagenesis and Resistance Selection[J].Microbiology,2007,34(5):0831-0835. |
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| Authors: | GUO Wei-Huan LI Xiao-Bing and YUAN Ying-Jin |
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| Institution: | Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072;Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072;Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072 |
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| Abstract: | |
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| Keywords: | Streptomyces lydicus Streptolydigin Complex mutagenesis Resistance selection |
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