| 神经肽Y和去甲肾上腺素在杏仁内侧核内影响血压和心率中的相互作用 |
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| 引用本文： | 王绍,朴哲范,夏映红, 韩弟文.神经肽Y和去甲肾上腺素在杏仁内侧核内影响血压和心率中的相互作用[J].中国应用生理学杂志,1995(4). |
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| 作者姓名： | 王绍 朴哲范 夏映红 韩弟文 |
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| 作者单位： | 长春白求恩医科大学生理学教研室，通化地区卫生学校 |
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| 基金项目： | 国家自然科学基金资助课题 |
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| 摘 要： | 分别向杏仁内侧核（ＭＡＮ）内微量注射去甲肾上腺素（ＮＡ）或神经肽Ｙ（ＮＰＹ）。ＮＡ引起血压升高，心率加快；而ＮＰＹ引起血压降低，心率减慢。如果注入不能改变血压的小剂量ＮＰＹ，则可抑制ＮＡ引起的升压作用，反映ＮＰＹ与ＮＡ共同参与心血管活动的中枢性调节过程。向ＭＡＮ中注射ＮＰＹ后血中ＮＡ的含量也相应降低，表明在ＭＡＮ中注射ＮＰＹ引起的血压、心率反应是通过降低血浆中ＮＡ含量而实现的。
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| 关 键 词： | 杏仁内侧核，神经肽Y，去甲肾上腺素，血压，心率 |
THE RELATIONSHIP OF NEUROPEPTIDE Y AND NORADRENALINE IN MEDIAL
AMYGDALOID NUCLEUS IN THE CARDIOVASCULAR REGULATION |
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| Wang Shao,Piao Jefan,Xia Yinghong.THE RELATIONSHIP OF NEUROPEPTIDE Y AND NORADRENALINE IN MEDIAL
AMYGDALOID NUCLEUS IN THE CARDIOVASCULAR REGULATION[J].Chinese Journal of Applied Physiology,1995(4). |
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| Authors: | Wang Shao Piao Jefan Xia Yinghong |
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| Abstract: | Experiments
were carried out in Wistar rats. Micro-injection of noradrenaline
(NA) intomediai amygadaloid nucleus(MAN)induced the rising of blood
pressure and increase in heartrate. Microinjection of neuropeptide
Y(NPY)into MAN caused decrease in blood pressure andheart rate. When
NPY at a dosage not inducing any change of blood pressure was used
before in-jection of NA the pressor effect of NA injected into MAN
was inhibited,indicating that NPY andNA had interaction in the
central regulation of cardiovascular activities.In the
meantime,injec-tion of NPY into MAN also induced decrease in the NA
concentration of peripheral blood. Itseems that the cardiovascular
effects elicited by injection of NPY into MAN are the results of
de-crease in NA in the peripheral blood. |
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| Keywords: | medial amygdaloid nucleus noradrenaline neuropeptide blood pressure heart rate |
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