Whole-genome sequences of four Mycobacterium bovis BCG vaccine strains |
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Authors: | Pan Yuanlong Yang Xi Duan Jia Lu Na Leung Andrea S Tran Vanessa Hu Yongfei Wu Na Liu Di Wang Zhiming Yu Xuping Chen Chen Zhang Yuanyuan Wan Kanglin Liu Jun Zhu Baoli |
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Affiliation: | Microbial Genome Research Center, CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, People’s Republic of China. |
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Abstract: | Mycobacterium bovis Bacille Calmette-Guérin (BCG) is the only vaccine available against tuberculosis (TB). A number of BCG strains are in use, and they exhibit biochemical and genetic differences. We report the genome sequences of four BCG strains representing different lineages, which will help to design more effective TB vaccines. |
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