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Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD
Authors:Peter L. Hsu  Fan Yang  Whitney Smith-Kinnaman  Wen Yang  Jae-Eun Song  Amber L. Mosley  Gabriele Varani
Affiliation:1 Department of Chemistry, University of Washington, Seattle, WA 98195, USA;2 Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
Abstract:
Keywords:CTD, C-terminal domain   PolII, polymerase II   NTD, N-terminal domain   DiFMUP, 6,8-difluoro-4-methylumbelliferyl phosphate   EDTA, ethylenediaminetetraacetic acid   BGP, β-glycerophosphate   CTR, C-terminal region   NOE, nuclear Overhauser enhancement   MPD, methyl-2,4-pentanediol   SeMet, selenomethionine
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