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Identifying biophysical assays and in silico properties that enrich for slow clearance in clinical-stage therapeutic antibodies |
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| Authors: | Boris Grinshpun Nels Thorsteinson Joao NS Pereira Friedrich Rippmann David Nannemann Vanita D Sood Yves Fomekong Nanfack |
| Institution: | aDiscovery & Development Technologies, Drug Disposition & Design, EMD Serono Research & Development Institute, Inc, Billerica, MA, USA;bDepartment of Scientific Services, Chemical Computing Group ULC, Montreal, Quebec, Canada;cDiscovery & Development Technologies, Drug Disposition & Design, Merck Healthcare KGaA, Darmstadt, Germany |
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