Phosphoryl amino acids: Common origin for nucleic acids and protein |
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| Authors: | Yu-Fen Zhao Pei-sheng Cao |
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| Institution: | (1) Department of Chemistry, Laboratory of Bio-organic Phosphorus Chemistry, Tsinghua University, 100084 Beijing, People's Republic of China |
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| Abstract: | A series of compounds (DAP-AA) composed of an amino acid (AA) and a dialkyl phosphoryl group (DAP) is the basic elements of life chemistry. Self-catalysis of DAP-AA gives the self-assembly oligopeptides, even in aqueous medium at 38°C. The oligo-nucleotides could also be assembled from nucleosides' phosphorylation by DAP-AA. DAP-AA acts as the energy source as well as the phosphoryl donor for the synthesis of nuclic Acids and protein. A general expression for the self assembly system is proposed. |
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| Keywords: | basic element of life chemistry model expression phosphoryl amino acids Origin of life |
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