Diversity of Superoxide-Dismutases Among Clinical and Soil Isolates of Streptomyces Species |
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| Authors: | Valérie Leclere Patrick Boiron Roland Blondeau |
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| Institution: | (1) Laboratoire de Microbiologie, Université des Sciences et Technologies de Lille, F-59655 Villeneuve d'Ascq Cedex, France , FR;(2) Unité de Mycologie, Institut Pasteur 25, rue du Dr Roux, F-75724 Paris, Cedex 15, France , FR |
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| Abstract: | Comparison of the nature, activity, and cellular localization of superoxide-dismutases (SOD) from soil and clinical isolates
of Streptomyces species was investigated to identify possible factors that could account for the pathological role of the strains isolated
from human lesions. Results showed that all of the studied strains possessed a cytoplasmic Ni-SOD. This particular SOD, found
in isolates from patients, could be a new taxonomic criterion to identify Streptomyces species with greater precision. A second minor SOD, assimilated to an Fe/Zn-SOD, was detected in some strains, but no relationship
was established between the presence of this enzyme and the clinical origin of the strains.
Received: 9 April 1999 / Accepted: 9 June 1999 |
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