一氧化氮与雄性生殖系统

一氧化氮是近年来发现的一种重要的生物信号分子和效应分子 ,在生物体内 ,L 精氨酸在一氧化氮合酶的作用下生成一氧化氮后 ,以自分泌或旁分泌形式作用于自身或邻近的细胞 ,发挥信号传导和细胞毒性等多种生理功能。近年来的研究表明 ,一氧化氮对雄性生殖系统上至下丘脑 ,下到性腺、附性器官都具有十分重要的生理调节作用。

Nitric Oxide in Male Reoroductive System

Nitric Oxide (NO), a recent-found messenger, is catalyzed from L-arginine, by Nitric oxide synthase (NOS) in the body of animals or human beings. NOSs distribute in almost all kind of organs or cells of animals studied so far and involve in numerous pathologic and physiologic processes. Researches in last few years revealed that NO plays a crucial role in reproduction systems at all levels from the brain to the gonads and even the accessory sex organs. In this review, we focus on its regulatory function on reproductive system of male mammalian.