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Human Chromosome 10 loci map to three different sheep chromosomes
Authors:H A Ansari  P D Pearce  D W Maher  T E Broad
Institution:(1) AgResearch, Grasslands Research Centre, Private Bag 11008, Palmerston North, New Zealand
Abstract:The interleukin 2 receptor (IL2RA), a human Chromosome (Chr) 10p locus, was mapped to sheep Chr 13q12-q15 by in situ hybridization. Two loci from human Chr 10q, cytochrome P450 subfamily XVII (CYP17) and the tachykinin 2 receptor (TAC2R), were assigned to sheep Chrs 22q21-q23 and 25q14-q23 respectively. The assignment of IL2RA allows the provisional assignment of the previously unassigned sheep syntenic group U15 to sheep Chr 13. Sheep linkage group 5 is predicted to be located on sheep Chr 25 on the basis of the TAC2R assignment.
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