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Targeted protein depletion in <Emphasis Type="Italic">Saccharomyces cerevisiae</Emphasis> by activation of a bidirectional degron
Authors:Marc Jungbluth  Christian Renicke  Christof Taxis
Institution:1.Department of Genetics,Philipps-Universit?t Marburg,Marburg,Germany
Abstract:

Background  

Tools for in vivo manipulation of protein abundance or activity are highly beneficial for life science research. Protein stability can be efficiently controlled by conditional degrons, which induce target protein degradation at restrictive conditions.
Keywords:
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