The flagellin gene of Borrelia miyamotoi sp. nov. and its phylogenetic relationship among Borrelia species |
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Authors: | Masahito Fukunaga Yasuyo Koreki |
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Institution: | Department of Molecular Microbiology, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Gakuencho 1-1, Fukuyama 729-02, Japan |
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Abstract: | Abstract We have cloned and sequenced the flagellin gene from Borrelia miyamotoi strain HT31 and compared it with previously published flagellin sequences. Sequence similarity analysis demonstrated that strain HT31 is phylogenetically distant from the three species of Lyme disease borreliae and is deeply branched into the relapsing fever borrelia cluster. The result was in full agreement with the classification of Borrelia strains using 16S rRNA sequences. This finding indicates that a phylogenetic analysis using flagellin gene sequences might be useful for classification of Borrelia strains. |
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Keywords: | Borrelia miyamotoi Spirochete Flagellin gene Phylogeny |
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