The dynamics of cytostatic factor production by inactivated resident peritoneal macrophages from Syrian hamsters]

Results presented indicate that resident peritoneal macrophages (Mph) of intact, or tumor-bearing Syrian hamsters release cytostatic factor(s) (CSF) independently on the presence of serum in culture medium and the degree of Mph adherence. Dynamics of CSF secretion and accumulation depends on the number of Mph and duration of time of CSF production. It has been shown that at later time of Mph cultivation (24 hours) supernatants examined can stimulate proliferation of the target cells.