BACA: bubble chArt to compare annotations |
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Authors: | Vittorio Fortino Harri Alenius Dario Greco |
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Institution: | .Unit of Systems Toxicology, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250 Helsinki, Finland ;.Nanosafety Centre, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250 Helsinki, Finland |
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Abstract: | BackgroundDAVID is the most popular tool for interpreting large lists of gene/proteins classically produced in high-throughput experiments. However, the use of DAVID website becomes difficult when analyzing multiple gene lists, for it does not provide an adequate visualization tool to show/compare multiple enrichment results in a concise and informative manner.ResultWe implemented a new R-based graphical tool, BACA (Bubble chArt to Compare Annotations), which uses the DAVID web service for cross-comparing enrichment analysis results derived from multiple large gene lists. BACA is implemented in R and is freely available at the CRAN repository (http://cran.r-project.org/web/packages/BACA/).ConclusionThe package BACA allows R users to combine multiple annotation charts into one output graph by passing DAVID website.Electronic supplementary materialThe online version of this article (doi:10.1186/s12859-015-0477-4) contains supplementary material, which is available to authorized users. |
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Keywords: | Enrichment analysis Visualize enrichment results R package |
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