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BACA: bubble chArt to compare annotations
Authors:Vittorio Fortino  Harri Alenius  Dario Greco
Institution:.Unit of Systems Toxicology, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250 Helsinki, Finland ;.Nanosafety Centre, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250 Helsinki, Finland
Abstract:

Background

DAVID is the most popular tool for interpreting large lists of gene/proteins classically produced in high-throughput experiments. However, the use of DAVID website becomes difficult when analyzing multiple gene lists, for it does not provide an adequate visualization tool to show/compare multiple enrichment results in a concise and informative manner.

Result

We implemented a new R-based graphical tool, BACA (Bubble chArt to Compare Annotations), which uses the DAVID web service for cross-comparing enrichment analysis results derived from multiple large gene lists. BACA is implemented in R and is freely available at the CRAN repository (http://cran.r-project.org/web/packages/BACA/).

Conclusion

The package BACA allows R users to combine multiple annotation charts into one output graph by passing DAVID website.

Electronic supplementary material

The online version of this article (doi:10.1186/s12859-015-0477-4) contains supplementary material, which is available to authorized users.
Keywords:Enrichment analysis  Visualize enrichment results  R package
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