Immunohistochemical investigation of different cytokeratins and vimentin in the human epididymis from the fetal period up to adulthood |
| |
Authors: | Dr Michael Kasper Peter Stosiek |
| |
Institution: | (1) Department of Pathology, District Hospital Görlitz, Görlitz, German Democratic Republic;(2) Pathologisches Institut, Bezirkskrankenhaus Görlitz, Girbigsdorfer Str. 1-3, DDR-8900 Görlitz, German Democratic Republic |
| |
Abstract: | Summary The anatomical distribution of cytokeratins and vimentin was investigated by means of immunohistochemistry in the human epididymis. Epithelial cells of the ductuli efferentes and the corpus epididymidis were positive for cytokeratins and vimentin. The expression of epithelial vimentin decreased toward the cauda epididymidis, whereas cytokeratins remained unchanged. The epithelium of the ductus deferens was negative when antibodies against vimentin were used. With monoclonal antibodies to individual cytokeratins, the presence of cytokeratins 7, 8, 18, and 19 was demonstrated histochemically throughout the epithelium of the epididymis. Monoclonal antibodies specific for cytokeratin 17 allowed immunohistochemical differentiation between the ductuli efferentes and the ductus epididymidis. |
| |
Keywords: | Epididymis Intermediate filaments Coexpression Cytokeratin Vimentin Human |
本文献已被 SpringerLink 等数据库收录! |
|