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High‐Resolution Molecular Validation of Self‐Renewal and Spontaneous Differentiation in Clinical‐Grade Adipose‐Tissue Derived Human Mesenchymal Stem Cells |
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| Authors: | Amel Dudakovic Emily Camilleri Scott M. Riester Eric A. Lewallen Sergiy Kvasha Xiaoyue Chen Darcie J. Radel Jarett M. Anderson Asha A. Nair Jared M. Evans Aaron J. Krych Jay Smith David R. Deyle Janet L. Stein Gary S. Stein Hee‐Jeong Im Simon M. Cool Jennifer J. Westendorf Sanjeev Kakar Allan B. Dietz Andre J. van Wijnen |
| Affiliation: | 1. Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota;2. Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota;3. Department of Health Sciences Research and Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota;4. Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota;5. Department of Medical Genetics, Mayo Clinic, Rochester, Minnesota;6. Department of Biochemistry, Vermont Cancer Center for Basic and Translational Research, University of Vermont Medical School, Burlington, Vermont;7. Department of Biochemistry, Rush University Medical Center, Chicago, Illinois;8. Institute of Medical Biology, A*STAR, National University of Singapore, Singapore;9. Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota |
| Abstract: | |
| Keywords: | MESENCHYMAL STEM CELL ADIPOSE‐TISSUE DERIVED STROMAL CELLS PLURIPOTENT MULTIPOTENT CELL CYCLE LINEAGE‐COMMITMENT FIBROBLAST OSTEOGENESIS CHONDROGENESIS ADIPOGENESIS HISTONE CYCLIN EXTRACELLULAR MATRIX CD44 CD73 NT5E CD90 THY1 CD105 ENG NES ACTA2 OCT4 POU5F1 NANOG KLF4 CCND1 CCNB2 HIST1H3H HIST1H4A HIST2H4A HIST2H4B E2F1 E2F7 E2F8 HINFP NPAT ASPN ECM2 FMOD OGN PODN WISP2 SFRP2 SFRP4 WNT2 WNT2A WNT5A WNT5B WNT7B RARRES2 TNNT3 ADH1B H19 CHI3L1 |