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A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity
Authors:Dong‐Hyun Kim  Zhen Xiao  Sanghoon Kwon  Xiaoxiao Sun  Daniel Ryerson  David Tkac  Ping Ma  Shwu‐Yuan Wu  Cheng‐Ming Chiang  Edward Zhou  H Eric Xu  Jorma J Palvimo  Lin‐Feng Chen  Byron Kemper  Jongsook Kim Kemper
Institution:1. Department of Molecular and Integrative Physiology, University of Illinois at Urbana‐Champaign, Urbana, IL, USA;2. Laboratory of Proteomics and Analytical Technologies, Advanced Technology Program, SAIC‐Frederick, Inc., National Cancer Institute‐Frederick, Frederick, MD, USA;3. Department of Statistics, University of Georgia, Athens, GA, USA;4. Simmons Comprehensive Cancer Center, Departments of Biochemistry and Pharmacology, University of Texas, Southwestern Medical Center, Dallas, TX, USA;5. Laboratory of Structure Sciences, Van Andel Research Institute, Grand Rapids, MI, USA;6. Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland;7. Department of Biochemistry, University of Illinois, Urbana, IL, USA
Abstract:
Keywords:acetylation  NF‐κ  B  PIASy  steatosis  SUMO2
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