新疆维吾尔自治区20年间胃癌的临床特点分析

目的:分析新疆地区近20年来胃癌流行病学特征,探讨其变化规律及发展趋势。方法:回顾性分析和比较1991年、2001年、2011年经新疆维吾自治区人民医院胃镜及病理学诊断确诊为胃癌的病例的一般资料、病理学及内镜下特点,包括性别、年龄、病理类型、发病部位。结果:1991年组:胃癌检出率为2.48%,中位年龄为54岁,男女之比为3.3:1.0,发病部位以胃窦部癌为主,占39.1%;2001年组:检出率为2.39%,中位年龄为61岁,男女之比为3.0:1.0,发病部位以胃体部癌为主,占42.1%;2011年组:检出率为1.48%,中位年龄为63岁,男女之比为3.9:1.0,发病部位以贲门胃底部为主,占34.8%。三组病理学类型均以腺癌为主,检出率有逐年升高趋势,但差异无统计学意义(P0.05)。结论:(1)近20年来胃癌发病部位有上移现象,且胃癌检发病率有下降趋势;(2)男性胃癌患者发病率明显高于女性,且近20年来胃癌患者男女比例无明显改变;(3)近20年来胃癌发病中位年龄逐渐增高,且随着年龄的增长发病率逐渐升高,以中老年发病率最高;(4)癌患者病理类型仍以腺癌为主,且近20年来腺癌所占比例无明显变化。

Clinical Charateristics of Gastric Carcinoma of Xinjiang Uygur Autonomous Region over the Past Twenty Years

Objective: To analyze the clinical charateristics of gastric carcinoma of Xinjiang Uygur Autonomous Region over the past twenty years, and investigate its variation and development tendency .Methods: The data of gastric cancers confirmed by gastroscope and pathology in 1991, 2001 and 2011 in the People''s Hospital of Xinjiang Uygur Autonomous Region were analyzed, including the gender, age, pathologic type, pathogenic site, etc. Results: 1991 groups: the detection rate of gastric cancer was 2.48%, the median age was 54 years old, the male-to-female ratio was 3.3:1, and had a higher incidence in gastric antrum,accounting for 39.1%; 2001 groups: the detection rate of gastric cancer was 2.39%, the median age was 61 years old,the male-to-female ratio was 3.0:1.0, and had a higher incidence in corpus,accounting for 42.1%; 2011 groups: the detection rate of gastric cancer was 1.48%, the median age was 63 years old,the male-to-female ratio was 3.9:1.0, and had a higher incidence in gastrocardiac carcinoma, accounting for 34.8% . Adenocarcinoma was the main histological type, and the detection rate was increasing trend,but the difference was not statistically significant (P>0.05).Conclusion: (1) The pathogenetic sites of gastric carcinoma had moved up, and the detection rate had declined in the past twenty years; (2)The male had a higher incidence rate than female, and the male-to-female ratio was not changed significantly. (3) The mean age of gastriccarcoinisma moved up, and with the increase of age, the incidence rate of gastric carcinoma rised, and old male had a higher incidence rate in the past twenty years; (4) adenocarcinoma had a higher incidence rate, and the percentage of adenocarcinoma was not changed significantly in the past twenty years.