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Binding site structure of one LRP-RAP complex: implications for a common ligand-receptor binding motif |
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| Authors: | Jensen Gitte A Andersen Olav M Bonvin Alexandre M J J Bjerrum-Bohr Ida Etzerodt Michael Thøgersen Hans C O'Shea Charlotte Poulsen Flemming M Kragelund Birthe B |
| Institution: | SBiN Lab, Institute of Molecular Biology and Physiology, University of Copenhagen, ?ster Farimagsgade 2A, DK-1353 Copenhagen K, Denmark. |
| Abstract: | |
| Keywords: | LRP low-density lipoprotein receptor-related protein LDL low-density lipoprotein RAP receptor-associated protein RAPd1 RAP domain 1 CR complement-type repeat EGF epidermal growth factor ER endoplasmatic reticulum NOE nuclear Overhauser effect NOESY NOE spectroscopy HSQC heteronuclear single quantum coherence AIR ambiguous interaction restraint DQF-COSY double-quantum filtered correlated spectroscopy TOCSY total correlated spectroscopy SPR surface plasmon resonance |
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