快速微波热声层析成像在生物医学中的潜在应用

介绍了一种快速热声层析成像方法和装置,成功实现了生物组织的二维热声层析成像及异物检测.实验中采用频率为1.2 GHz的脉冲微波作为激发源,中心频率为3.5 MHz的320振元线性阵列探测器接收热声信号,然后用有限场滤波反投影方法重建得到热声层析图像.与原有方法相比,勿需全方位扫描采集数据,能大量节省时间,重建图像的对比度和抗噪声能力有极大提高.该方法和系统有望应用于乳腺癌早期检测、体内异物检测、微波热疗效果监测等方面.

Fast Microwave-induced Thermoacoustic Tomography and the Application in Biomedicine

A thermoacoustic tomography system was developed and used to reconstruct tissue image and detect foreign body.The frequency of the microwave used in the system is 1.2 GHz.The microwave absorption image can be reconstructed through signals received by the 320 transducer elements with mid-frequency 3.5 MHz.A phase-controlled focus technique is used to reduce data acquisition time and a limited-field-filtered back-projection algorithm is used to enhance spatial resolution and signal to noise rate.This system has a potential to use in the detection of early breast tumor,foreign body and microwave thermotherapy effect monitoring.